Learning @ ISTM
CISTM17 - Alan Magill Memorial Lecture: Pathogenesis of Cerebral Malaria: Lessons Learned at the Bedside
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While the precise mechanisms of cerebral malaria (CM) pathogenesis remain unclear, groundbreaking studies performed in Malawi have given us insight into the pathogenesis of CM in children. A distinctive retinopathy in children with coma is a sensitive and specific indicator of sequestration of infected RBCs in the brain. Significant advances in our understanding of CM have been achieved through magnetic resonance imaging (MRI) studies, which indicate that brain swelling is the cause of death in CM. During this session, Dr. Taylor will walk us through her teams groundbreaking research which has helped our understanding of CM.
• Discuss the clinical presentation of pediatric cerebral malaria (CM).
• Review retinopathy associated with CM.
• Review neuroimaging findings and cause of death in pediatric CM.
• Discuss future interventions to help improve mortality in CM.